So, just to clarify, are you looking for a GUI tool in which to develop Lite-C applications? Or are you asking if Lite-C can be used to create a GUI?

Lite-C can generate GUI elements for your game.

3DGS comes with a tool to edit Lite-C - called SED. I haven't used Visual C, so it's probably not exactly what you're looking for. But it lets you edit your scripts, and has all sorts of nice features, like debugging, commenting, and auto-tabbing. These are the main things I use, but I'm sure there are lots of other features that can help you program...

Also, WED (Level Editor) allows you to visually put together levels, models and scripts, kind of like Unity 3D.

The biggest limitation of 3DGS / Lite-C is that it only allows you to develop Windows applications, where other languages/editors allow porting to other platforms.