Thanks very much for your feedback guys! I've been working on polishing the logic a bit further and I've been able to extract a few more routines into helper functions (that keeps the run() function cleaner and easier to follow). I'll post the code below.

Next I'm going to work on dynamic switching of parameter ranges depending on the asset. My thinking is that if I incorporate a reasonable parameter range that is also personalized for each asset... that it could have a major impact.

Code:
function fridayClose(int fridayclose)
{
	//allows Friday trading up until NYSE 3pm; close trades and don't allow after this
	if(fridayclose && dow() == FRIDAY && lhour(ET) >= 15) 
		{
			exitLong("*");
			exitShort("*");
			return 1; //condition met; indicate no further trades
		}
	return 0; //condition not met; safe to take new trades
}

function hourOpen(int hourblockstart, int hourblockend)
{
	//blocks new open trades between selected hours
	//uses NYSE time, including DST
	if ( (lhour(ET) >= hourblockstart) && (lhour(ET) < hourblockend) )
		return 0; //between blocked hours, do not allow trade opens
	else
		return 1; //no conditions met, allow trades by default
}

function todayOpenCombo(var dayopencombo)
{
	//allows optimizer to specify the best combo of days for opens
	//bit position 0 = Monday
	//bit position 1 = Tuesday
	//bit position 2 = Wednesday
	//bit position 3 = Thursday
	//bit position 4 = Friday
	//bit position 5 = Sunday
	//given a combination #, the function will return whether
	//current dow() is in the combination

	int dayopencombobits = dayopencombo+.5; //truncate to rounded int
	int today = dow() - 1; //Mon is 0
	if (today == 6) today = 5; //bump Sun to 5 (no Sat, keep binary range 0-63)

	if (dayopencombobits & (1 << today)) return 1; //current dow() is in the combo
		else return 0; //current dow() not in combo, do not allow trade opens
}

function todayCloseCombo(var dayclosecombo)
{
	//allows optimizer to specify the best combo of days to close by NYSE 4pm
	//bit position 0 = Monday
	//bit position 1 = Tuesday
	//bit position 2 = Wednesday
	//bit position 3 = Thursday
	//bit position 4 = Friday
	//bit position 5 = Sunday
	//given a combination #, the function will determine if we are beyond
	//a combo close time, close all trades if necessary, and return 1
	//if no further trades allowed today

	int dayclosecombobits = dayclosecombo+.5; //truncate to rounded int
	int today = dow() - 1; //Mon is 0
	if (today == 6) today = 5; //bump Sun to 5 (no Sat, keep binary range 0-63)

	if ((dayclosecombobits & (1 << today)) && lhour(ET) >= 16) 
	{
		exitLong("*");
		exitShort("*");
		return 1; //current dow() is in the combo; indicate no further trades
	}
	else return 0; //current dow() not in combo, safe to take new trades
}

function marketOpenCombo(var marketopencombo)
{
	//allows optimizer to specify best markets to initiate trades
	//bit position 0 = New York 8am-5pm Eastern
	//bit position 1 = Sydney 5pm-2am Eastern
	//bit position 2 = Tokyo 7pm-4am Eastern
	//bit position 3 = London 3am-12pm Eastern
	//given a combination #, the function will determine if current time is within
	//a market part of the combination (returns 1 to allow trading if true)
	
	int marketcombobits = marketopencombo+.5; //truncate to rounded int
	if ( (lhour(ET) >=8) && (lhour(ET) <17) && (marketcombobits & (1 << 0)) ) return 1; //inside New York
	if ( (lhour(ET) >=17) || (lhour(ET) <2) && (marketcombobits & (1 << 1)) ) return 1; //inside Sydney
	if ( (lhour(ET) >=19) || (lhour(ET) <4) && (marketcombobits & (1 << 2)) ) return 1; //inside Tokyo
	if ( (lhour(ET) >=3) && (lhour(ET) <12) && (marketcombobits & (1 << 3)) ) return 1; //inside London
	return 0; //default - current market not in combination, don't allow trade opens
}

function checkEquity(var emode)
{
	//emode 1 = standard: sets phantom/normal mode only (via Lots)
	//emode 2 = switch hitter: always in market (Lots=1), fades direction (via dir)
	//emode 3 = reward success with weighting: increase trades based on degree of improvement
	//emode 4 = mean reversion: trade when equity curve falls (Lots=1), sit out when it rises (Lots=-1)
	vars EquityCurve = series(EquityLong+EquityShort); //includes all phantom equity
	var dir; //indicates normal trade direction (dir=1) or reverse (dir=-1)

	//narrower curves
	//var slow = 50;
	//var fast = 10;

	//wider curves
	//var slow = 100;
	//var fast = 10;

	//mega-wide curves
	var slow = 200;
	var fast = 10;

	//uber-wide curves
	//var slow = 300;
	//var fast = 10;

	//optimized curves
	//var slow = optimize(50,50,300,12);
	//var fast = 10;

	vars EquityLP = series(LowPass(EquityCurve,fast));
	var EquityLPfalling = LowPass(EquityLP,slow);
	var EquityLPrisingBigger = LowPass(EquityLP,slow*3.2);
	var EquityLPrisingBig = LowPass(EquityLP,slow*1.5);
	//plot("EquityLPslow",LowPass(EquityLP,slow),1,BLUE);
	//plot("EquityLPfast",LowPass(EquityLP,fast),0,GREEN);
	
	if(EquityLP[0] < EquityLPfalling && falling(EquityLP)) { //drawdown
		if (emode==1) Lots = -1; //set phantom trade mode
		if (emode==2) return 1; //fade: take signals when losing
		if (emode==3) { //reward success with weighting
			Lots = -1; //set phantom trade mode
			return 1; //allow max 1 phantom trade in drawdown
		}
		if (emode==4) Lots = 1; //mean-reversion: start trading when equity curve falls
		
	}
	else { //positive equity curve
		if (emode==1) Lots = 1; //set normal trade mode
		if (emode==2) return -1; //fade: take reverse signals when winning
		if (emode==3) { //reward success with weighting
			Lots = 1; //set normal trade mode
			if (EquityLP[0] > EquityLPrisingBigger && rising(EquityLP)) return 3; //very big rising
			else if (EquityLP[0] > EquityLPrisingBig && rising(EquityLP)) return 2; //big rising
			else return 1; //rising but not yet significantly
		}
		if (emode==4) Lots = -1; //mean-reversion: stop trading when equity curve rises
	}
}

function checkTradesPerCycle()
{
	//require minimum 30 trades per WFO cycle or stop training
	static int LastWFOCycle = 0, LastNumTrades = 0;
	if(Train && (WFOCycle != LastWFOCycle) )
	{
		if(LastNumTrades > 0 and LastNumTrades < 30)
		{
			char tradecount[100];
			sprintf(tradecount,"Not enough trades per cycle: %d",LastNumTrades);
			quit(tradecount);
		}
		LastWFOCycle = WFOCycle;
	}
	LastNumTrades = NumWinTotal+NumLossTotal;
}

function calculateMargin(int direction)
{
	//calculate risk Margin based on OptimalF and trade direction
	Capital = 1000; //simulated account balance
	var riskCapital = 600; //basis to trade with
	
	if (direction && OptimalF>.001) //long trade, historically profitable
		return OptimalFLong * riskCapital;
	else if (!direction && OptimalF>.001) //short trade, historically profitable
		return OptimalFShort * riskCapital;
	else if (is(TRADEMODE)) //non-historically profitable = phantom live trades only
		Lots = -1;

	return 0; //no Margin allocated for non-historically profitable
}

function checkModifiers()
{
	int reversedir = 0; //default normal trade direction (0) unless specified otherwise
	int fridayclose = 0; //enforce auto-close and no trades after NYSE 3pm Friday
	int hourblockstart = 0; //block trade opens beginning at NY hour
	int hourblockend = 0; //block trade opens ending at NY hour
	int dayopencombo = 63; //optimize(54,1,63,1); //combo of days to open; 63=every day
	int dayclosecombo = 0; //optimize(33,1,63,1); //combo of days to close after NYSE 4pm; 0=none; 63=every day
	int marketopencombo = optimize(12,1,15,1); //combo of markets to allow trade opens; 15=every market

	if ( (!fridayClose(fridayclose) //close NYSE 3pm on Friday
		|| !todayCloseCombo(dayclosecombo) ) //close NYSE 4pm on selected days
		&& todayOpenCombo(dayopencombo) //open on selected days only
		&& marketOpenCombo(marketopencombo) //open during selected markets only
		&& hourOpen(hourblockstart,hourblockend) ) //open during selected hours only
			return 1; //ok to place new trades
	else
		return 0; //no trade, restricted by a modifier	
}


function run()
{
	set(PARAMETERS+FACTORS);
	StartDate = 20080101;
	EndDate = 20130531;
	BarPeriod = 15;
	LookBack = 600;
	DataSplit = 70; //70% training, 30% OOS test
	NumWFOCycles = 5;
	if(is(TESTMODE)) NumSampleCycles = 15; //oversampling on Test only, not Train
	if (Train) { RollLong = 0; RollShort = 0; } //help prevent asymmetry in parameters & profit factors
	checkTradesPerCycle(); //stop Train early if not enough trades
	int maxtrades = 1;
	int reinvestprofits = 1; //invoke margin setting during trade logic

	//equity-curve trading
	checkEquity(1); //emode 1: normal/phantom trading
	//reversedir = checkEquity(2); //emode 2: switch hitter
	//maxtrades = checkEquity(3); //emode 3: reward success
	//checkEquity(4); //emode 4: mean-reversion mode
   
   while(asset(loop("NZDJPY","EURUSD","AUDUSD","AUDCHF","AUDJPY","USDCHF","USDJPY")))
	{
		//edge trading logic
		var TimeCycle = optimize(64,55,75,1,0);
		var TimeFactor = optimize(2.6,0.2,5,0.2,0);
		//Stop = BarPeriod*PIP; //simple stop level
		Stop = ATR(200) * optimize(1.99,1,15,0.5,-3); // allow 3% tolerance for preferring low stop distances
		Trail = ATR(200) * optimize(8.5,3,13,0.5);

		vars Price = series(price(0));
		vars MA1 = series(SMA(Price,TimeCycle));
		vars MA2 = series(SMA(Price,TimeCycle*TimeFactor));

		if (checkModifiers())
		{
			//OK to trade, let's evaluate signals then
			if (crossOver(MA1,MA2) && rising(MA1))
			{
				if (reinvestprofits) Margin = calculateMargin(1); //long
				//enterLong(); //standard entry
				reverseLong(maxtrades);
			}
			else if(crossUnder(MA1,MA2) && falling(MA2))
			{
				if (reinvestprofits) Margin = calculateMargin(0); //short
				//enterShort(); //standard entry
				reverseShort(maxtrades);
			}
		}
	}

	PlotWidth = 1100;
	PlotHeight1 = 800;
}