Ive just done a bit of research, and it SHOULD work for COM1 right through to COM256
The core API functions should allow this, according to several on-line sources.
But I dont have a USB device that will let me 'set' it above COM8 to test with ATM.
Im gonna try and beg/borrow/steal one in the next few days and I'll post my results...
FYI :: be certain you are trying to access the ports with COM in capital letters, and be sure there is no trailling "."
ie "COM25" is correct, but NOT "com25" or "COM25."