I just asked for this in another thread and was told that the difference should be marginal. If it is not, there could be a large randomness in the strategy. I face this problem even on daily bars and I'm not quite sure how to handle it.
Don't know which thread it is so I'll continue in this one...
I don't think there's much randomness in the strategy I'm testing. It's a simple mean reversion strategy based on SMA and hourly data. It makes hundreds of trades per year so some minor differences should be lost in the large sample.
It's this one (you can check it and judge for yourself):
http://people.brandeis.edu/~blebaron/wps/fxnyc.pdf
If anyone's interested I can paste the code too.