Hmmm yes, this should be possible i guess, because C# functions are called from the engine, for example in ent_create or when events occur !
But I don't really see a need for lite-c if you use C# ! The only thing were you really need (from what i know) lite-c instead of C# is for declaring bitmaps which you use in shader (at least i know of no workaround for this..). You can also access all engine objects like entities and modify them in C#, the wrapper also has a scheduler, similar to the one in lite-c ! Did you have a look at the examples at the wrapper homepage ? http://acknexwrapper2.matthias-auer.net/
If you got more questions don't hesitate to post or e-mail them !